Bone-marrow derived vascular precursors are an important endogenous repair reservoir for vascular repair and neovascularization. Therapies of stem/progenitor cells targeting on angiogenesis are considered hopeful solutions for tissue repair and regeneration. However, the dysfunction of patient-derived progenitor cells has been implicated in diabetes, which limits the efficacy of autologous cell therapies in the clinic.

In a recent project, researchers from Wayne State University used LC Sciences’ miRNA microarray service to report the different microRNA expression profiles in bone marrow-derived progenitor cells from type 2 diabetic mice and their normal controls.

Related Service

miRNA Microarray Service – LC Sciences provides a miRNA expression profiling service using microarrays based on our in-house developed µParaflo® technology platform. We have standard arrays for all mature miRNAs of all species available in the latest version of the miRBase database (Release 21, July 2014). Our service is comprehensive and includes sample labeling, array hybridization, image data processing and in-depth data analysis. Two-three weeks after receiving your total RNA samples, we’ll send you both the raw and fully analyzed data. [Learn more…]

Reference

J.M. Wang, K. Zhang (2016) Microarray analysis of microRNA expression in bone marrow-derived progenitor cells from mice with type 2 diabetes Genomics Data 7:86-7. [article]