Interest in RNA modifications has grown rapidly in recent years, including N6 methyl adenosine modification (m6A), the most common methylation modification in mRNA. Methylated RNA immunoprecipitation sequencing (MeRIP-seq), is a convenient method for detection of these and other post-transcriptional RNA modifications. Note that MeRIP-seq can identify m6A hypermethylated regions but does not achieve single base resolution.
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Our Comprehensive Services Offer
The latest in next-gen sequencing technology
Experienced staff to assist you with experimental design
Fast turnaround times
Full bioinformatics analysis
Expert technical support to assist with data interpretation
In-Depth Data Analysis Includes:
Alignment, classification, & functional annotation of all mapped reads
Biostatistical analysis – expression analysis, multi-parameter data analysis, length distribution, transcript copy number comparisons, etc
Peak calling on whole genome
Differential methylation
Motif identification
Differential expression analysis of mRNA
Correlation between RNA-seq and m6A-seq
GO & KEGG enrichment analysis of diff genes/peaks
Analysis Pipeline
Turnkey Solution
These comprehensive services are designed to be one-stop and produce the results needed to quickly advance your biological and biomedical research. For all types of RNA sequencing, our “Total RNA to Data” services include: sample prep/QC, library preparation, RNA sequencing, bioinformatics analysis, and high-level customer support.
Expert Services
LC Sciences has been providing RNA discovery, profiling and related bioinformatics services since 2005 and our experts have examined thousands of varied RNA datasets, giving us unique insight into RNA research. We don’t merely deliver data; we will handle all the advanced bioinformatics analysis and help you find answers to the questions you’re asking.
LC Sciences has been providing RNA discovery, profiling and related bioinformatics services since 2005 and our experts have examined thousands of varied RNA datasets, giving us unique insight into RNA research. We don’t merely deliver data; we will handle all the advanced bioinformatics analysis and help you find answers to the questions you’re asking.